Blood value reveals the risk of blood clots

A simple blood test may reveal your risk of blood clots.

Blood value reveals the risk of blood clots

After age 50, the risk of blood clots in the legs increases sharply, especially for those who additionally belong to one or more of the risk groups.

Despite the fact that in recent years a number of risk factors have been identified, there is still some uncertainty.

Half of those who have a blood clot have no known risk factors.

However, a new study from Tromsø now appears to have revealed yet another factor.

Registered blood clot cases

As a part of the Tromsø survey, blood samples were taken from over 25 in 1994 and 1995. 000 inhabitants in Tromsø. One of the blood tests gave us a percentage of variation in the size of the red blood cells (RDE), says researcher, student Trygve Sølberg Ellingsen at K. G. Jebsen TRC Center for Thrombosis Research.

The study participants were then divided into groups based on the RDW value, and further all cases of venous blood clots were registered up to 1. January 2012.

– Thus we could compare the different groups with regard to blood clot risk, explains Ellingsen.

One quarter

Symptoms of blood clot in the legs

  • tenderness
  • Swelling
  • Spent skin
  • Heating
  • Reddening
  • Pain relief when the leg is raised and kept calm

Source: Pharmacy 1

The most common risk factors for blood clot

  • Smoking
  • Pregnancy
  • OCs
  • Hereditary Factor
  • Surgery
  • Sedentary or sedentary life
  • Long flights and buses
  • Cancer
  • Overweight
  • Previous thrombosis

Source: Professor David Russell

What is venous blood clot?

Venous blood clot will say blood clot in the veins – or blood vessels that carry oxygen-low blood back to the heart.

As a rule, the blood clot is formed in a vein of the leg and is called deep venous thrombosis.

Source: UiT Health Blog

According to Ellingsen, the results showed that significantly more of those in the highest RDW value group developed blood clots than those in the lowest-value group.

– With the help of statistical models, we have adjusted the risk estimates for other known risk factors, so we have been given an estimate of how much RDW represents, he says..

One quarter of the study participants had such high values ​​that the researchers thought it gave increased risk.

– It does not mean that one in four has cause for concern. The risk of venous blood clots is generally low, and it is still, although it increases slightly. As a rule, several risk factors need to take place before risk increases significantly, says Ellingen.

There is also a genetic variation that increases the risk of blood clots. It got click journalist Nina’s experience when she took a gentest.

Normal blood test

The blood sample it is talking about is a part of so-called blood counting, and one of the most commonly used blood tests in hospitals and in general practice.

– For now, we can only say that there is a correlation between variation in blood cell size and risk of blood clot. What this connection is, however, is not mapped, he says.

According to Ellingsen, the result does not provide clinical value before the causes of the relationship are known.

– Further studies are required to investigate which value differs best between high and low value and the meaning of variation in blood cell size in interaction with other risk factors for blood clot. Hopefully, we will get more answers to these questions in the coming years, he says.

Shipping to the lungs

Blood clot affects today about 8-10. 000 Norwegians every year.

– The risk of blood clots depends on age. In young people one of 100. 000 get blood clots, while one in 100 older people gets it, says Ellingsen.

As a rule, the blood clot is formed in a vein of the leg and is called deep venous thrombosis.

– If part of the blood clot loosens, it can bring blood flow through the heart to the lungs. This is called pulmonary embolism and is a serious condition, he says.

Venous blood clots are the third most common and fatal among cardiovascular diseases.

In other words, many deaths can be avoided with early and targeted prevention, he says.

Use support stockings

There are several things you can do to reduce the risk of blood clots and it is important to be aware that if you have more risk factors, they reinforce each other.

– First, you should avoid smoking and exercise regularly. It is also important that after surgical procedures you get back in motion quickly. Whether you’re walking or moving your arms and legs while lying in bed, says Professor at the Neurological Department at the University of Oslo, David Russell.

He also states that compression stockings have a good effect against blood clots after surgery.

Such support stockings can also be used preventively if you are in a hurry, are pregnant or if you are going to travel a lot like aircraft.

Blood value reveals the risk of blood clots

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Key Results

According to the professor, the results from Tromsø could mean a lot for patients without risk factors, which would otherwise not be caught and given treatment on time.

– This study is very interesting. Previously, smaller studies have shown similar results, but the study from Tromsø includes a large number of audiences in Tromsø municipality. However, it is important that more studies are conducted so that you can be sure of the findings, he says.

According to Russell, further study should also investigate the mechanism behind the results.

Should start early

Blood value reveals the risk of blood clots

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– Half of those who have venous blood clots have no known risk factors. Therefore, there is a need and great gain in uncovering new risk factors, he says.

Detecting risk factors makes it easier for doctors to start with preventive treatment in those patients who benefit most from it.

– Preventative treatment has the greatest effect when it starts early, and it is important to provide the right person to the right person, says Russell.



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