Protects against genital warts and precursors of cervical cancer.
If girls between 16 and 26 years of age are vaccinated against Human Papillomavirus (HPV), the number of women who develop cervical cancer precursors is reduced by 20 percent, says a method assessment conducted by the National Knowledge Center for Health Services.
It is a recommendation for all women to take this vaccine.
Cervical cancer usually develops in about 10-30 years. Irregular bleeding can be due to cancer of the lining of the lining or in the cervix.
HPV vaccination was incorporated into the Norwegian childhood vaccination program in 2009, as an offer for girls aged 11-12 years.
The background for the method assessment is that the National Institute of Public Health now considers recommending so-called vaccination vaccination for girls older than 12 years when the HPV vaccine offer was introduced, which today is 17-26 years.
HPV infection is the most common sexually transmitted infection in the world.
But why 26, and what about women over 26 years ?, Ask Click Health.
– The majority of clinical trials have been done among women up to 26 years, but this figure may be a bit randomly chosen, says Jeanette Stålcrantz, Senior Advisor at the Department for Medicine, National Public Health Institute, to Click Health..
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The point is that the older you stay, the greater the likelihood that you have already been infected with HPV and therefore the effect of vaccinating will be less. This does not mean that women older than 26 years will not receive a protective effect by vaccinating, but it will be an individual assessment, in line with the general assumption that the vaccine has the best effect for those who have not been sexually active or who is HPV naive (acc. Knowledge Center), says Stålcrantz.
Should be recommended for more
The Knowledge Center itself does not provide recommendations, but sums up research into the impact of various measures, and their reports are used as part of the decision-making basis when recommendations are to be given, for example, in the form of guidelines.
– The Norwegian Institute of Public Health agrees that the vaccine should be recommended for more than it is recommended to today, but it will thus be an individual assessment of whether older women should take the vaccine. What is important is that women, vaccinated and non-vaccinated, follow the screening program for cervical cancer and investigate themselves as recommended in the Cancer Registry’s guidelines, says Stålcrantz.
HPV vaccine up to 45 years
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The Norwegian Institute of Public Health is responsible for the Norwegian child welfare program and their starting point is that it is important for girls to take the HPV vaccine before being exposed to infection so that they get the best effect of the vaccine. The HPV vaccine Gardasil is nevertheless approved for use in women up to 45 years.
– That the vaccine only works for those who have not been sexually active or have been infected is a myth. It has been documented a good preventive effect up to 45 years, “says Sveinung Sørbye, chief physician at the Department of Clinical Pathology at the University Hospital Northern Norway (UNN), who has even lectured on the vaccine for other doctors.
Although the vaccine does not cure established cell changes, it has also been documented that after the infection has passed (and any cell changes have resolved), the HPV vaccine will be able to protect against re-infection and new infections.
– It is a study that shows effect in women up to 45 years of age. We can therefore recommend vaccination up to the age, agrees Jone Trovik, head of the Norwegian Gynecological Association.
Free HPV vaccine
– There is no reason why a woman over 45 years old should not take HPV vaccine beyond any economic considerations. It is not harmful and can provide a useful protection. At the same time, it is more uncertain what protection you get, the greater the likelihood that you have been infected, adds Hanne Nøkleby, acting division director at the Division for Pollution Control, the National Institute of Public Health.
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Nøkleby further says that Sørbye is correct that there is no absolute yes or no response and that cervical cancer progression takes time.
Often it takes 30 years, and then you can discuss what benefits you get from the vaccine at the age of 60, if you want to spell it a little.
– When we make our assessments, we always add an assessment of the likelihood of utility, perhaps a little more than those who only see one and one patient and think about whether there might be a potential for this patient to earn anything on taking the vaccine. I think it is the background for the shade difference in our and W. Sørbyes answer, because it’s just a shade, says Nøkleby.
– With regard to retrieval vaccination, there is probably no cost / benefit analysis that only supports it until the age. We would like to support the introduction of public retrieval vaccination, but initially not so high in age, Trovik also says.
– The vaccine is a recommendation for all. With regard to what is cost-effective for society, there is a limit of 26 years when it comes to providing a free HPV vaccine. On the other hand, women who are single can benefit from the vaccine even when they are grown ups, but then they have to pay for themselves, says Sørbye.
HPV vaccine, cell sample and HPV test
In view of the best possible prevention of cervical cancer, all women should take HPV vaccine, take a cell test and assess HPV test, says senior South-born, supported by Professor Ivar Sønbø Kristiansen, professor at the Department of Health Management and Health Economics, University in Oslo, a department that works a lot with screening of, among other things, cervix.
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In the AN-column “Nordland’s trumpet” they write that the background for the recommendation is the disappointing reality that the cell sample is uncertain for several reasons. The cell sample has probably halved the number of cases of cervical cancer, but each year still gets about. 300 women detected this type of cancer and about 150 of these women have taken a cell test and about 70 have only had normal cell samples.
All women 25-69 years old, however, are advised to accept the cervical cell sample every three years to detect cell changes that can lead to cervical cancer at an early stage.
– Cell test is not an alternative to a vaccine, but can contribute to early detection of cellular changes, that is, cancer precursors. Cancer can be prevented by eliminating these, says Sørbye.
Protects against four HPV types
In the case of HPV testing to check your own HPV status, this will probably replace today’s cell sample in a few years. Then you will be able to discover some more precursors that are currently being overlooked.
– Most HPV tests used today are used to find women with cellular changes, not to find all women with HPV infection, says South Africa and continues:
Women do not notice the disease as men do
– An HPV vaccine will nevertheless not affect an ongoing infection. The HPV vaccine Gardasil also prevents infection of four different HPV types. It is possible to be infected with several HPV types at once, but it is unlikely that you are infected with all four types at once.
Most HPV infections perish within two years. A naturally reviewed HPV infection will provide little protection against later HPV infections, even not of the same HPV type, but the HPV vaccine provides good protection against later infection. The HPV vaccine will prevent future infection of all four HPV types if the body is able to get rid of current infection.
For more information from the Folhehelseinstituttet, see fhi. no, and would you like to put yourself in the documentation that General Sveinung Sørbye refers to, is this available in the Facebook group YES thanks, to the HPV vaccine.
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Two vaccines against HPV infection have been developed. The vaccine consists of artificially produced particles that resemble parts of the surface of true HPV virus. The vaccine is not alive, does not contain viral tissue and can not cause HPV infection.
The HPV vaccine protects against HPV types 16 and 18. These are the two types that usually give cervical cancer (responsible for 70 percent of cases). One of the vaccines (Gardasil) also protects against HPV types 6 and 11, which causes 90 percent of all genital warts (condylomas). Since the vaccine only protects against about 70 percent of the carcinogenic HPV types, it is very important that women who are allowed to vaccinate nevertheless continue to follow the cervical cancer screening program..
HPV vaccine was included in the 7th Infant Children’s Infant Program. grade from the school year 2009-2010. So far Gardasil has been used in the program. With regard to the collection of vaccines, the Ministry of Health and Care Services determines this and it is currently uncertain whether and when such a vaccination vaccination will be relevant in Norway.
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Older girls and women can get from their GP, gynecologist or others who do a vaccination, for example at a health center for youth. The vaccine is placed with syringe in the arm and you must have three doses. Generally, the second dose is given two months after the first and the last dose is given six months after the first dose. Vaccine today costs between 3000-3500 kroner for all three doses.
Source: National Public Health Institute, fhi. com
HPV infection and cancer
HPV infection is the most common sexually transmitted infection in the world, and about 70 percent are infected with a genital HPV infection one or more times during life (of those who are sexually active). Some of the sexually transmitted species are harmless and are not labeled, while others may cause genital warts. There are high risk HPV types that can provide different forms of cancer in both women and men, which are prerequisites for the development of cervical cancer. In addition to women’s cervical cancer, cancer in the external genitals of women and the rectum of both sexes is mainly caused by HPV. Cancer in the penis and the oral cavity and throat may be associated with HPV infection.
Source: National Public Health Institute, fhi. com
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