The first symptoms are often skin change or skin rash.
<psoriasis is a skin disease that causes red rash with whitish, scaly crusts. Psoriasis may occur throughout the body, but is more frequently observed on the legs and arms, especially on the elbows and knees, scalp, hands and feet, face of the hairline or around the nose and eyebrows, back and chest, nails, armpits, groin and other skin folds.
The spread of the rash varies depending on what type of psoriasis you have and how seriously you are. Now new studies show that skin disease can be associated with cardiovascular disease.
– It is clear that psoriasis is associated with a higher risk of cardiovascular disease such as myocardial infarction and stroke. The severity of psoriasis affects this risk, says dermatologist Cato Mørk at Akershus Dermatological Center in Lørenskog, in a report on psoriasis.
He describes psoriasis as a systemic disease, ie the disease attacks multiple organs simultaneously.
– Mild forms of psoriasis have no increased risk, but moderate and severe cases of skin disease have up to three times the risk of cardiovascular disease. Traditional risk factors such as obesity, high blood pressure and diabetes are often reported in patients with psoriasis, which can explain the increased risk, says Mørk and continues:
However, the chronic inflammatory reaction to psoriasis is also important. Signal molecules that promote inflammation are elevated by both psoriasis and cardiovascular disease.
Furthermore, he says that a large study concludes that psoriasis itself increases the risk of cardiovascular disease after the other risk factors have been corrected.
There has also been evidence of increased mortality of cardiovascular disease in severe psoriasis, especially in younger patients if compared to healthy people of the same age, “says Dark..
It appears in his report that changes in some of the genes associated with psoriasis are also linked to increased risk of cardiovascular disease.
This can worsen or trigger psoriasis:
* Other skin diseases.
* Self-reported stress.
May be hereditary
Psoriasis gives a kind of skin inflammation that causes rashes. Pharmaceutical in Vitusapotek, Åse Storfjell-Olven, says that inheritance can play an important role for who gets this skin disease.
– Why someone gets psoriasis is not known, but legacy is of importance. About half of those who get psoriasis have someone in the family with it. Psoriasis is a disease that fluctuates between good and bad periods, she says to Click Health.
She also tells about factors that can exacerbate or provoke psoriasis.
– Some medicines, such as lithium, chlorokin and beta blockers can affect skin disease. Similarly, the skin disease is also affected by smoking, alcohol, stress and periods of severe mental stress, “explains Storfjell-Olven.
The first symptoms are often skin changes or skin rashes.
– There are various forms of psoriasis, and it is very individual how powerful one is being hit. It can be a particularly challenging disease for those who are severely affected and periodically have to be treated in hospitals, “she says..
Action against the disease
Psoriasis is a chronic disease, and thus there is no cure that causes permanent healing of psoriasis. On the other hand, there are a number of measures that can cause skin strokes to go back and keep the disease at bay. General Secretary of Psoriasis and Eczema, Terje Nordengen, presents possible solutions.
– In order for the results to be successful, it is necessary that you take responsibility for the treatment yourself. Self-treatment in terms of good skin care is an important basis that should be performed regularly if you have a lot of rashes. In periods of bloating of the symptoms, most people will need to use drugs, he says to Click Health.
Depends on severity
There are a lot of medicines for psoriasis, and what type of treatment depends, among other things, on what type of psoriasis you have, where on the body you have the disease and how intense it is.
– The drugs exist in different variants. Many in the form of cream or ointment, others like liquid, while some are taken as tablets or in syringe form. In addition, light treatment and sun treatment in combination with saltwater baths are effective for many with psoriasis, he says.
The goal of all treatment of psoriasis is to alleviate the plagues, keep the disease under control over time and prevent unnecessary excessive quality of life. At the same time, you want the side effects to be small and insignificant.
Nordengen tells about current psoriasis drugs:
* Vitamin D analogues:
Calcipotriol or calcitriol, often in combination with cortisone, are widely used anti-psoriasis drugs. The effect is good for most people and the preparation has few side effects. The substances are closely related to vitamin D, and are also called vitamin D3 analogues. This comes as a jelly or ointment and should be lubricated once a day.
* Local Coordinator:
Corticosteroids contain cortisone and are a group of drugs that work by damping inflammation of the skin. They relieve pain, itching and discomfort caused by psoriasis. This is found in many different varieties and strengths, as well as creams, ointments and liquids.
* Immunosuppressive treatment:
In people who are heavily plagued by psoriasis and where regular treatment with creams and ointments is insufficient, it may be appropriate to attempt immunosuppressive treatment, which is a mild form of chemotherapy. Such treatment is often very effective, but can also cause some side effects.
* Biological Treatment:
TNF-alpha is a substance in the body that plays a key role in initiating and maintaining skin inflammation in psoriasis. Drugs containing anti-TNF-alpha can thus provide a rapid and sustained recovery of the disease. The treatment is offered to patients with widespread and severe psoriasis where other treatment has not given a satisfactory effect.
– The disadvantage is that these are expensive medicines for which you do not know all long-term side effects. In the long run, these drugs will be safe to use, while the price will be lower. Thus, there will be a better treatment for more people with severe psoriasis, “says Nordengen.